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Primarily, our in vitro investigations employed the AML12 and HL7702 cell lines, which, despite their widespread use, do not entirely mimic primary hepatocyte behavior

In these mice, IGF1 overexpression was not sufficient to prevent the decrease in muscle mass induced by hind-limb unloading [46]

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This result indicates that activity of Sm TG expressed in the GCI strain was enhanced because of the higher glutathione content present when compared with that of the BY4741 strain